Thursday, September 15, 2022

September 15

I'm tired. But want to record some positive developments from today.

First, while at lunch with J, I got to talking about the ways to make myself more productive. I said something to the effect of: "I need to remove the barriers to getting started as much as possible...and finish as much as possible!" It's a matter of recognizing that a lot of what you put out into the world isn't going to be perfect, and that's okay. The idea is that we'll get a lot better, faster, if we pump out some imperfect stuff, than if we obsess over small details and produce only a few things. I feel like I put those principles into action, to a limited extent, today. I took care of some small nagging things.

Second, I skimmed an interesting 2012 review in Science by Roman Stocker about bacteria mixing in the ocean. It's his most-cited paper. Interestingly, the subject of mixing by ocean bacteria is scarcely mentioned. And that reminded me of the AHTF project, and one of the myriad reasons I am interested in it. (along with the fact that John Dabiri, at least as of 2018, also did not know of any studies looking into micromixing of heat by bacteria). I wonder if I should reach out to Roman or to Anupam. The latter might be down to make this into a fun collaboration! 

Third, I read a fascinating paper on the use of PslGh and PelAh hydrolases to disrupt biofilms. I wonder if we could do better with DNA NPs. I was especially excited to see that this could conceivably help lower the cost of treating wounds. I wonder if GHs and DNANPs can be somehow made cheaply?

Fourth, I need to remember to schedule a time to do something (implementation intention), and then do it without making much fuss. Many things I could accomplish at 80% in the time that it takes to fuss about trying to do it at 100%.

I need to remember to spend most of my time and energy on what fascinates me.

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